NOXious Phosphorylation
نویسندگان
چکیده
منابع مشابه
Nociceptors—Noxious Stimulus Detectors
In order to deal effectively with danger, it is imperative to know about it. This is what nociceptors do--these primary sensory neurons are specialized to detect intense stimuli and represent, therefore, the first line of defense against any potentially threatening or damaging environmental inputs. By sensing noxious stimuli and contributing to the necessary reactions to avoid them--rapid withd...
متن کاملTREKing noxious thermosensation
The ability to sense environmental temperature as pleasant or unpleasant is associated with the activity of thermo-sensitive neurons in the peripheral nervous system. Differential sensation of pleasant environmental temperatures (warm and cool) versus unpleasant and noxious (cold and hot) temperatures requires the definition of thresholds and temperature ranges for activating thermonociceptors....
متن کاملNOXious phosphorylation: Smooth muscle reactive oxygen species production is facilitated by direct activation of the NADPH oxidase Nox1.
N ADPH oxidases of the Nox family are important sources of reactive oxygen species (ROS). Nox-derived ROS serve multiple functions in the organism, but in the healthy vascular system they are primarily signaling molecules. Numerous cytokines, growth factors, and hormones have been shown to stimulate Nox-dependent ROS production as essential step in their signal transduction. 1 Seven catalytical...
متن کاملSelective adaptation to noxious foods
feeding by herbivorous insects. Some of these noxious compounds are both unpalatable and toxic, while others are merely unpalatable or toxic (Bernays and Chapman, 1987; Chapman and Sword, 1994; Glendinning, 1996; Harley and Thorsteinson, 1967). Because many plants concentrate noxious compounds in their most nutritious tissues (McKey, 1979), herbivores would benefit from an ability to adapt to f...
متن کاملDyspnea as a noxious sensation: inspiratory threshold loading may trigger diffuse noxious inhibitory controls in humans.
Dyspnea, a leading respiratory symptom, shares many clinical, physiological, and psychological features with pain. Both activate similar brain areas. The neural mechanisms of dyspnea are less well described than those of pain. The present research tested the hypothesis of common pathways between the two sensations. Six healthy men (age 30-40 yr) were studied. The spinal nociceptive flexion refl...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2014
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.114.305280